Raw Peptides Delta Sleep-Inducing Peptide Bodybuilding Dsip Raw Powder
Product Name:Delta sleep-inducing peptide,DSIP
DSIP CAS NO:62568-57-4
DSIP Molecular Formula:C35H48N10O15
DSIP Molecular Weight:848.81
DSIP Grade:pharmaceutical grade
In vitro it has been found to have a low molecular stability with a half life of only 15 minutes due to the action of a specific aminopeptidase-like enzyme.It has been suggested that in the body it complexes with carrier proteins to prevent degradation, or exists as a component of a large precursor molecule,but as yet no structure or gene has been found for this precursor.
Many roles for DSIP have been suggested following research carried out using peptide analogues with a greater molecular stability and through measuring DSIP-like immunological (DSIP-LI) response by injecting DSIP antiserum and antibodies
Roles in endocrine regulation
Decreases basal corticotropin level and blocks its release.
Stimulates release of luteinizing hormone (LH).
Stimulates release of somatoliberin and somatotrophin secretion and inhibits somatostatin secretion.
DSIP Structure and Interactions
DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C
It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.
Evidence supports the current belief that it is regulated by glucocorticoids.
Gimble et al. suggest that DSIP interacts with components of the MAPK cascade and is homologous to glucocorticoid-induced leucine zipper (GILZ).GILZ can be induced by Dexamethasone. It prevents Raf-1 activation, which inhibits phosphorylation and activation of ERK.
Shipping method: super discreet packaging, to ensure safe delivery, 99% successful delivery rate is ensured.
Delivery time: All of the orders will be packed within 24 hours after we get the payment
usually it takes about3~5work days for you to get the parcel.
Payment method: Bank wire, Western union, Moneygram
Order: For large volume clients, substantial discounts can be arranged on an individual basis.
No Trick, No Scam. We are here at your service at any time.
We don’t do business with people who don’t mutual trust in their minds. We are doing sensitive business,
if you feel unsafe to send us funds, please go find the one you trust most. Good business is only for people who deserve it.
Our answer is to guarantee delivery worldwide.
The United States, New Zealand, Australia, Germany, Norway, Switzerland and Canada customers Also to ensure delivery