99.5% Body Building Polypeptide Sexual PT 141 Lyophilized Powder (10mg/Vial)
IPT-141, sometimes referred to as PT-141 and most recently under the name Bremelanotide is a peptide hormone that derived from Melanotan II. Melanotan II (MT2) was developed for the purpose of promoting tanning, but more than 90% of all subjects during testing were found to have increases in libido, performance and sexual satisfaction. These effects held true in both men and women tests subjects with the enhanced effect of male erection function being the most surprising.
IPT-141 Functions and Traits
IPT-141 is a peptide hormone of the synthetic class based on the alpha-melanocyte-stimulating hormone (alpha-MSH). IPT-141 binds at the melanocortin receptors, which are found to directly affect the area of the central nervous system (CNS). The effect on the CNS has been shown to greatly increase libido in men and women, as well as sensitivity and satisfaction. It also appears to have a positive effect on erectile dysfunction (ED). However, ED that is caused by blood flow issues may not be improved with this peptide, but IPT-141 seems to have a stronger impact on erections when their lack of quality is based on other factors. Researchers then isolated the part of MT2 that caused this effect and developed the peptide IPT-141, Bremelanotide. Palatin Technologies, the original patent holders of Bremelanotide have stated the effects of IPT-141 on sexually related effects are approximately 50 times greater than MT2.
IPT-141 will be found in freeze-dried form and is to be reconstituted using bacteriostatic water. The peptide can be injected intramuscularly or subcutaneously depending on user preference. Total use in terms of dose and duration, there is no official data available, only internet conjecture.
Treatment of Sexual Dysfunction
Bremelanotide or PT-141 is the generic term for a new research peptide for use in helping improve sexual dysfunction in men (erectile dysfunction or impotence) as well as helping improve sexual dysfunction in women (sexual arousal disorder).
PT-141 is a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.Bremelanotide, PT-141 does not act on the vascular system like the former compounds but it is known and has been shown to help increase sexual activity in both male and female mammals. Bremelanotide PT-141 allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation.
Bremelanotide is a novel treatment that could potentially change the face of treating sexual disorders, not only because of its effectiveness due to a unique mode of action, but also due to its safety and the fact it works synergistically with other ED/SAD treatments.
Bremelanotide is effective in its potential to treat sexual desire disorders as well as disorders that affect physical arousal. Bremelanotide induces lordosis in animal subjects, a sign of physical preparation for copulation. In males, it does not stimulate the vascular aspect of the penis, but instead acts to stimulate the central nervous system primarily via dopamine receptor activity to increase sexual desire and also demonstrates functionality in treating purely physical manifestations of ED/SAD, likely through improved signalling.
Co-administration of PT-141 and Sildenafil
Bremelanotide also offers potential as a low-dose concurrent treatment with low-dose sildenafil.
The erectile response induced by co-administration of PT-141 and sildenafil was significantly greater than the response elicited by administration of sildenafil alone. Co-administration of PT-141 and sildenafil was safe and well-tolerated and did not result in new adverse events or adverse events that were increased in frequency or severity compared with monotherapy. Co-administration of intranasal PT-141 and a phosphodiesterase type 5 inhibitor may constitute a treatment alternative for patients in whom higher doses of a single therapy are not effective or well tolerated.
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